mtFIT study
Multitarget FIT study...
Description
The mulitarget FIT study is a prospective study that is running within the Dutch National CRC screening program. The aim of this study is to compare the performance of a new stool test (mtFIT) with the currently used FIT. In this study we collect the...
General Design
- Type
- Biobank, Clinical trial, Cohort study
- Cohort type
- Population cohort
- Data collection type
- Prospective
- Design
- Cross-sectional
- Design description
- Multi-target FIT or mtFIT clinical trial is a prospective study with paired design, embedded within the Dutch colorectal cancer (CRC) screening organization (more details: RIVM – Bevolkingsonderzoek darmkanker), referred to as SO in this document, which targets a cohort of men and women aged 55 to 75 years. The study objective is to compare the multi-target fecal immunochemical test (mtFIT) with standard FIT (Figure 2). The aimed sample size is 13,300 participants. Each participant hands in two test tubes: a standard one (i.e., FOB-Gold FIT) which is analyzed within the regular pipeline of the screening program and the second is an OC-Sensor tube which is used for mtFIT analysis. Both tests will be analysed in one of the laboratories involved in the FIT analysis for the national screening program. The data collection for the study is done in a collaboration between the Dutch screening organization (Facilitaire Samenwerking Bevolkingsonderzoeken FSB) through their ScreenIT national system.
- Design schematic
- Design schematic
- Start/End data collection
- not available
Population
- Countries
- Netherlands (the)
- Number of participants
- 13300
Organisations
Lead organisations
- Netherlands Cancer Institute (NKI)
Contributors
- Beatriz CarvalhoNetherlands Cancer Institute
Principal Investigator, Primary contact
- Lana Meiqari
Data manager
Dataset variables
Datasets
Datasets and their description
| Name | Description | |
|---|---|---|
No results for current selection |
Dataset variables
Dataset variables and their description
| variable | Dataset | |
|---|---|---|
No results for current selection |
Subpopulations
List of subpopulations for this resource...
| Name | Description | Number of participants | |
|---|---|---|---|
No results for current selection |
Collection events
List of collection events defined for this resource...
| Name | Description | Participants | Start end year | |
|---|---|---|---|---|
No results for current selection |
Networks
Part of networks...
Access conditions
- Data access conditions
- health or medical or biomedical research
- disease specific research
Funding & Acknowledgements
- Funding
- A Stand Up to Cancer–Dutch Cancer Society International Translational Cancer Research Dream Team Grant. Stand Up to Cancer is a program of the Entertainment Industry Foundation administered by the American Association for Cancer Research [SU2C–AACR–DT1415, MEDOCC]. Support for this study was also provided by the Dutch Digestive Foundation, and was co-funded by the PPP Allowance made available by Health_Holland, Top Sector Life Sciences & Health, to stimulate public-private partnerships (LSHM 15040, LSHM18032-SGF and LSHM21042). In LSHM21042, CRCbioscreen B.V., a spin-off company of the Netherlands Cancer Institute acts as a private partner providing cash matching.